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Biogen Inc. (BIIB)

POSITIVE
HealthcareDrug Manufacturers - GeneralUnited States

Fundamental

64

Price

$221.22

Market Cap

$32.23B

Part 1 · What the company is worth

Overview

Biogen develops and sells prescription medicines for neurological diseases: multiple sclerosis, spinal muscular atrophy, rare neuromuscular disorders and, through a partnership with Japan's Eisai, Alzheimer's disease. It discovers or licenses a drug candidate, runs the clinical trials required for approval, then manufactures and markets the medicine once regulators clear it. Its founding franchise of multiple sclerosis drugs, once the core of the business, is now shrinking as patents expire and cheaper alternatives reach the market, while newer rare-disease and Alzheimer's treatments are still building toward a comparable scale.

How it makes money

Revenue comes almost entirely from selling drugs once a patient starts a treatment course, plus royalties and profit-sharing from partnered products such as the Alzheimer's drug Leqembi, sold jointly with Eisai. Contract manufacturing for other companies adds a smaller, steadier stream. Because each drug needs years of costly trials before it can be sold, profitability depends on a handful of approved products carrying the cost of the whole research pipeline; when an older drug loses patent protection, its price and volume can fall quickly as cheaper copies enter the market.

Competitive moat

Patents and licences · Narrow

Biogen's business rests on patents and regulatory exclusivity for its drugs, which briefly block generic competition. That protection is temporary and running out fast: its largest multiple sclerosis products are already being undercut by biosimilars and generics. Newer drugs for rare diseases and Alzheimer's offer some renewed protection, but none yet replaces the scale of the franchise it is losing.

What drives demand

Defensive

Demand for treatments of chronic, often life-threatening neurological conditions does not disappear in a recession: patients keep taking medicines they need. What moves faster is which drug they take and at what price, as insurers, government payers and biosimilar makers push down what Biogen can charge for its older products once exclusivity ends.

Key risks

  • Loss of exclusivity on core MS drugs — Tysabri and Spinraza, still among Biogen's largest products, are past or nearing the end of their patent protection, and biosimilar or generic competition has already eroded sales of older multiple sclerosis drugs such as Tecfidera and Avonex.
  • Dependence on the Eisai partnership for Leqembi — Leqembi, Biogen's Alzheimer's drug, is developed, marketed and largely controlled jointly with Eisai; its commercial success depends on decisions, execution and reimbursement work that Biogen does not fully control.
  • Clinical and regulatory risk — Turning a drug candidate into approved revenue requires clinical trials that can fail at any stage, and a positive trial result is still no guarantee that regulators will approve the drug or that payers will reimburse it.
  • Pricing pressure from governments and payers — Government drug-pricing programs, and the negotiating power of insurers and pharmacy benefit managers, can reduce what Biogen is paid for a drug well after it reaches the market, without warning.
  • Dependence on a narrow group of growth products — Recent growth depends on a small set of newer drugs — Leqembi, Skyclarys, Zurzuvae and Qalsody — that must keep growing fast enough to offset the decline of the older franchise, a transition still underway and not yet complete.

The case for

Buyers argue that Biogen's newer rare-disease drugs and its Alzheimer's franchise with Eisai are growing fast enough to replace the declining multiple sclerosis business, and that a specialized neurology pipeline still holds unproven optionality.

The case against

Sellers fear that legacy multiple sclerosis revenue is eroding faster than new products can replace it, that Leqembi's commercial ramp depends on factors outside Biogen's control, and that the next wave of pipeline drugs may fail in trials before they ever reach the market.

Written by the editors, published on August 18, 2026

Direct competitors

Who this company fights with for the same customers

No editorial profile for this company yet

No competitor list for this company yet.

Balance Sheet & Liquidity

Revenue

$9.94B

Trailing 12 months (through 3/31/2026)

Net Income

$1.37B

Trailing 12 months (through 3/31/2026)

Free Cash Flow

$2.05B

Total Equity

$18.26B

Total Liabilities

$11.18B

Current Ratio

3.06

Interest Coverage

-

Debt/EBITDA

3.83

Earnings Per Share

Revenue & Net Income

Free Cash Flow

Income Breakdown

Historical statement

Margins over time

Debt over time

How heavy the debt is

Growth grid

Growth — Revenue

Fair Value Estimation

Undervalued

Fair Value

$309.05

Current Price

$221.22

Margin of Safety

+28.4%

Fair Value Range

$200.89 - $417.22

Estimation Methods

Analyst Target:$235.57
DCF:$804.75
PE-based:$79.08
Graham Growth:$42.19
EPV:$72.65
Analyst Consensus:Buy (29B / 13H / 1S)
Last Earnings Surprise:+19.75%

Valuation Metrics

P/E Ratio

23.45

ROE

7.1%

P/B Ratio

1.73

P/FCF

13.29

Gross Margin

75.5%

ROIC

-

Profitability Radar

Value Creation (Economic Moat)

ROIC

-

WACC

6.1%

ROIC − WACC

-

Fundamental Analysis Criteria

Passed (16)

  • EPS shows upward trend
  • EPS CAGR 8.60%
  • Gross Margin 75.5%
  • P/FCF 13.29
  • P/B Ratio 1.73
  • Debt/Equity ratio
  • Positive Free Cash Flow
  • CapEx intensity
  • Current Ratio
  • Debt/EBITDA
  • Return on Tangible Assets
  • Analyst Consensus 67% Buy
  • Earnings Surprise avg 22.1%
  • Earnings Quality (OCF/NI) 1.89
  • Share Dilution 0.7%
  • Piotroski F-Score 6/9

Failed (7)

  • Price CAGR -2.65%
  • Low reliance on intangibles
  • Price below Graham Number
  • DCF valuation (Fairly valued)
  • ROE 4.5%
  • Revenue Growth 5Y -6.0%
  • Net Margin Trend 13.8% vs 15.1%

Unavailable (5)

  • ROIC NaN%
  • Dividend Payout NaN%
  • Operating Margin NaN%
  • Interest Coverage
  • PEG Ratio (need PE > 0 and growth > 0)

Piotroski F-Score

6/9

Mixed signals: some areas need attention

score
criteria

Earnings Quality

1.89

High quality: earnings backed by cash

Share Dilution

0.7%

Share count is stable

Governance

Executive Team

NameTitleAge
Mr. Christopher A. ViehbacherPresident, CEO & Director64
Ms. Robin C. KramerExecutive VP & CFO59
Ms. Nicole MurphyExecutive VP and Head of Pharmaceutical Operations & Technology52
Dr. Priya Singhal M.D., M.P.H.Executive VP & Head of Development57
Mr. Sean GodboutVP, Chief Accounting Officer & Global Corporate Controller51
Mr. Guy HadariChief Information Officer-
Mr. Tim Power M.B.A., Ph.D.Head of Investor Relations-
Ms. Natacha GassenbachChief Communication Officer & Head of Corporate Affairs-
Mr. Adam Keeney Ph.D.Executive VP & Head of Corporate Development48
Dr. Ginger Gregory Ph.D.Executive VP & Chief Human Resources Officer57

Audit Risk

8

Board Risk

2

Compensation Risk

9

Shareholder Rights Risk

2

Part 2 · The price and when to enter

This part won't tell you whether the company is worth owning: it helps you choose when to buy it, once the fundamentals have convinced you. Inside: technical analysis, potential, historical drawdowns, gamma exposure.

Latest News

Recent headlines for BIIB, sourced from Markets Gazette.

  • 6/18/2026POSITIVE
    Biogen To Acquire RayThera For Up To $1 Billion, Expanding Immunology Pipeline

    Biogen Inc. has announced its intention to acquire RayThera for a sum potentially reaching $1 billion. This strategic move aims to bolster Biogen's immunology pipeline, signaling a diversification strategy beyond its established focus on Alzheimer's disease. The acquisition of RayThera's early-stage assets is expected to enhance Biogen's long-term growth prospects and competitive positioning in the biopharmaceutical sector. Investors will be closely watching the integration process and the development of the newly acquired pipeline candidates.

  • 5/14/2026NEGATIVE
    Why Is Biogen Stock Falling Thursday?

    Biogen Inc. (BIIB) shares experienced a decline on Thursday following the release of mixed Phase 2 clinical trial data for its Alzheimer's drug, diranersen. While the drug showed some cognitive benefits, the overall results were not as strong as anticipated, leading to investor caution. Despite the setback, several analysts have maintained an optimistic outlook, highlighting the potential of diranersen's cognitive benefits and suggesting that the drug could still represent a significant advancement in Alzheimer's treatment. This mixed sentiment creates uncertainty for investors regarding the drug's future development and market potential.

  • 5/6/2026NEUTRAL
    Biote Q1 2026 Earnings Call: Complete Transcript

    Biogen Inc. held its Q1 2026 earnings call on May 6, 2026. The call provided a comprehensive overview of the company's financial performance and strategic outlook for the upcoming periods. While the transcript is available, specific financial figures, performance metrics, or forward-looking statements that would indicate a clear positive or negative market impact were not detailed in the provided summary. Investors should refer to the full transcript for in-depth analysis of the company's results and future guidance.

  • 4/7/2026POSITIVE
    Biogen Taps Alloy Platform To Push Antisense Drug Pipeline Forward

    Biogen has entered into a strategic partnership with Alloy Therapeutics, leveraging Alloy's proprietary platform to accelerate the development of its antisense drug pipeline. This collaboration focuses on advancing RNA-targeting therapies, a key area of innovation for Biogen. The agreement is expected to enhance Biogen's drug discovery and development capabilities, potentially leading to novel treatments for neurological diseases. For investors, this move signifies a commitment to expanding the company's therapeutic offerings and strengthening its position in the biotechnology sector, potentially unlocking future revenue streams.

  • 4/1/2026POSITIVE
    Biogen Buys Apellis for $5.6B to Expand Kidney Drugs

    Biogen Inc. has announced a definitive agreement to acquire Apellis Pharmaceuticals for $5.6 billion in cash and stock. This strategic move significantly bolsters Biogen's presence in the immunology sector, with a particular focus on expanding its portfolio of treatments for rare kidney diseases. The acquisition, one of Biogen's largest to date, is expected to leverage Apellis's established drug pipeline and commercial infrastructure. Investors may view this as a positive step towards diversification and long-term growth for Biogen, potentially enhancing its market position in specialized therapeutic areas.

via Markets Gazette